Jun-Ichi Kira Selected Research

Connexin 30

8/2018	Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson's disease animal model.
1/2018	Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia.

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Jun-Ichi Kira Research Topics

Disease

33	Multiple Sclerosis 01/2022 - 05/2004
18	Demyelinating Diseases (Demyelinating Disease) 06/2021 - 11/2010
15	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 01/2021 - 08/2013
11	Neuromyelitis Optica (Devic's Disease) 01/2021 - 01/2013
10	Polyneuropathies (Polyneuropathy) 11/2020 - 10/2015
8	Inflammation (Inflammations) 01/2021 - 05/2004
8	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2020 - 11/2006
7	Myelitis 06/2021 - 05/2004
6	Relapsing-Remitting Multiple Sclerosis 06/2017 - 12/2012
5	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2021 - 02/2015
5	Neuralgia (Stump Neuralgia) 01/2021 - 11/2016
5	Muscle Weakness 01/2021 - 04/2004
4	Alzheimer Disease (Alzheimer's Disease) 04/2022 - 01/2017
4	Neuroinflammatory Diseases 06/2021 - 08/2017
4	Pain (Aches) 01/2020 - 01/2018
4	Stroke (Strokes) 11/2019 - 12/2016
4	Guillain-Barre Syndrome 11/2019 - 08/2013
3	Necrosis 01/2021 - 11/2010
3	Hypertrophy 01/2021 - 10/2015
3	Heart Failure 10/2020 - 10/2016
3	Muscular Diseases (Myopathy) 10/2020 - 05/2009
3	Cognitive Dysfunction 01/2020 - 01/2016
3	Ischemic Stroke 11/2019 - 12/2016
3	Atrophy 06/2019 - 04/2004
3	Hyperalgesia 01/2019 - 11/2016
3	Infections 01/2019 - 02/2004
3	Parkinson Disease (Parkinson's Disease) 08/2018 - 01/2017
3	POEMS Syndrome (Syndrome, POEMS) 10/2016 - 06/2008
3	Paraproteinemias (Monoclonal Gammopathy) 10/2016 - 06/2008
3	Opticospinal Multiple Sclerosis 01/2016 - 05/2004
2	Leukocytosis (Pleocytosis) 10/2022 - 04/2010
2	Motor Neuron Disease (Primary Lateral Sclerosis) 12/2021 - 01/2018
2	Aspiration Pneumonia 01/2021 - 01/2018
2	Multiple System Atrophy 12/2020 - 01/2017
2	Cerebral Hemorrhage 07/2020 - 05/2020
2	Thrombosis (Thrombus) 05/2020 - 11/2016
2	Arterial Occlusive Diseases (Arterial Occlusive Disease) 05/2020 - 12/2016
2	Ischemia 01/2020 - 01/2018
2	Insulin Resistance 01/2020 - 01/2017
2	Deglutition Disorders (Dysphagia) 01/2018 - 04/2010
2	Ataxia (Dyssynergia) 01/2018 - 11/2016
2	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2017 - 06/2007
2	Encephalitis (Encephalitis, Rasmussen) 11/2016 - 04/2010
2	MERRF Syndrome (Myoclonic Epilepsy and Ragged Red Fibers) 10/2016 - 06/2002
2	Fever (Fevers) 10/2016 - 04/2010

Drug/Important Bio-Agent (IBA)

24	AntibodiesIBA 01/2021 - 05/2004
21	Immunoglobulin G (IgG)IBA 11/2021 - 04/2010
19	Proteins (Proteins, Gene)FDA Link 10/2022 - 06/2003
11	AutoantibodiesIBA 01/2021 - 11/2010
7	Connexin 43 (Connexin43)IBA 06/2021 - 11/2011
7	AntigensIBA 01/2019 - 06/2008
6	HLA-DRB1 Chains (HLA DRB1)IBA 12/2021 - 01/2020
6	CytokinesIBA 01/2021 - 01/2013
6	Intravenous Immunoglobulins (IVIG)FDA Link 01/2021 - 04/2010
5	HLA Antigens (Human Leukocyte Antigens)IBA 11/2021 - 10/2012
5	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 11/2010
5	Biomarkers (Surrogate Marker)IBA 12/2020 - 01/2016
5	EnzymesIBA 12/2016 - 03/2007
4	Peptides (Polypeptides)IBA 11/2021 - 01/2018
4	plexinIBA 01/2021 - 01/2018
4	Prednisolone (Predate)FDA LinkGeneric 10/2020 - 04/2010
4	Complement System Proteins (Complement)IBA 01/2020 - 11/2010
4	Myelin-Oligodendrocyte GlycoproteinIBA 01/2020 - 01/2016
4	ChemokinesIBA 11/2019 - 01/2013
3	HLA-DRB1*04 antigenIBA 12/2021 - 01/2016
3	ConnexinsIBA 06/2021 - 01/2020
3	AllergensIBA 01/2021 - 06/2008
3	Aquaporin 4IBA 01/2020 - 08/2017
3	LectinsIBA 01/2020 - 02/2015
3	Immunoglobulin E (IgE)IBA 11/2019 - 05/2004
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2019 - 01/2017
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2018 - 04/2010
3	Natalizumab (Tysabri)FDA Link 06/2017 - 01/2017
3	ImmunosorbentsIBA 12/2016 - 03/2007
2	GoldIBA 10/2022 - 01/2018
2	Monoclonal AntibodiesIBA 01/2022 - 01/2017
2	Interleukin-13IBA 01/2021 - 11/2019
2	Interleukin-4 (Interleukin 4)IBA 01/2021 - 11/2019
2	Interleukin-10 (Interleukin 10)IBA 01/2021 - 11/2019
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2021 - 01/2018
2	Interleukin-8 (Interleukin 8)IBA 01/2021 - 01/2017
2	Fingolimod Hydrochloride (FTY720)FDA Link 07/2020 - 01/2017
2	Tissue Plasminogen Activator (Alteplase)FDA Link 07/2020 - 11/2019
2	Tacrolimus (Prograf)FDA LinkGeneric 05/2020 - 10/2019
2	Amyloid (Amyloid Fibrils)IBA 01/2020 - 01/2017
2	Interleukin-6 (Interleukin 6)IBA 11/2019 - 01/2017
2	Mitochondrial DNA (mtDNA)IBA 04/2019 - 10/2016
2	BQ 788IBA 01/2019 - 11/2016
2	Connexin 30IBA 08/2018 - 01/2018
2	Glutamic Acid (Glutamate)FDA Link 01/2018 - 01/2017
2	Superoxide Dismutase-1IBA 01/2018 - 02/2015
2	Dimethyl FumarateIBA 01/2018 - 08/2017
2	Levodopa (L Dopa)FDA LinkGeneric 01/2018 - 12/2006
2	GadoliniumIBA 06/2017 - 12/2012
2	SteroidsIBA 01/2017 - 01/2012
2	Thalidomide (Thalomid)FDA Link 10/2016 - 01/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2016 - 01/2015

Therapy/Procedure

18	Therapeutics 05/2020 - 03/2004
7	Immunotherapy 10/2020 - 12/2004
2	Thrombectomy 08/2021 - 12/2016